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How Does Biotage Develop Sustainable Science?

Biotage: A Global Impact Tech Company

Biotage — a Sweden-based, “Global Impact Tech Company” — puts sustainability first by developing sustainable science that makes the world a healthier, cleaner, and greener place to live. The company is built on the concept of “Humankind Unlimited”, a concept that puts solving society’s problems first.

To accomplish this, Biotage offers solutions and products assisting in analytical sample preparation and testing, drug discovery and development, and water and environmental testing workflows.

These products and solutions apply to a broad range of customers in different divisions of life sciences, including biotech, contract research, pharmaceutical companies, contract manufacturers, academic institutions, forensic, and clinical laboratories. Additionally, the ‹rgets organizations focused on clean water, food safety, and environmental sustainability.  

Biotage is headquartered in Uppsala, Sweden. It has a rich history of developing life sciences instruments for more than 50 years. After a series of mergers and acquisitions, including Biotage LLC, Personal Chemistry, and International Sorbent Technologies (IST), the Biotage AB was formed in 2003 by Pyrosequencing.  

Today, the company has a global customer reach, with 485 employees working worldwide. Its CEO and president is Tomas Blomquist. 

In this article, we will review the range of products offered by Biotage AB, its services, and the resources it offers to its customers assisting in their variety of lab workflows.

Excedr’s lease program has provided a creative financial solution for many laboratories working on a budget. Lease the cutting-edge lab equipment you need, save capital for other parts of your business, and achieve R&D milestones quicker.

Biotage Product Portfolio 

Biotage manufactures and delivers a range of high-quality life sciences and pharma equipment, including chromatography systems, filtration units, evaporators, purification systems, and other consumables and diagnostic tools.

According to the type of workflow, Biotage products and consumables are categorized into different groups.

Organic Workflow

Biotage offers a variety of systems, accessories, and consumables for every step of organic synthesis, including purification, synthesis, and evaporation steps. 

A few examples of products are Biotage® Initiator+ for organic synthesis, ISOLUTE® SCX-2 to speed up analytical chemistry, Biotage® Selekt for flash chromatography, and Biotage® V-10 Touch for evaporation.

Peptide Workflow

Biotage has developed a spectrum of products for peptide synthesis workflow, including synthesis, purification, and evaporation. 

It offers single and multi-channel peptide synthesizers, High-Performance Flash Chromatography (HPFC) tools, and a V-10 series of evaporators that remove cleavage cocktails in less than 15 minutes.   

Scale-up Flash Purification

For any commercial-scale production, safety and robustness are key factors. Biotage offers solutions to scale up the purification of target molecules during flash chromatography.

Its Flash 75/150/400 and Isolera LS lab-based flash systems are reliable, require less maintenance, and run smoothly for years. 

Sample Preparation

Biotage provides a wide range of sample preparation solutions in the fields of clinical & bioanalytical, environmental, forensics & toxicology, food & agriculture, and doping control in animals & humans.

Whether you need to remove matrix components from biological samples, target drugs and small molecules for extraction, or extract semi-volatile organic compounds (SVOCs) from clean drinking water, Biotage’s sample preparation solutions can meet all your requirements. 

An example of the product in this category is the Biotage® Extrahera™ Classic. It’s an automated solution for Solid Phase Extraction (SPE), Supported Liquid Extraction (SLE), Protein Precipitation (PPT), and Phospholipid Depletion (PLD).

Biomolecule Purification

Biotage provides a range of tools to purify biomolecules, such as lipids, oligonucleotides, DNA, and RNA, for applications involving mRNA vaccines and gene therapy.

It provides solutions for antibody purification, enhancing oligosaccharides detection by HPLC, purification of tagged proteins, gel filtration, ion exchange, and reversed phase chromatography workflows. 

Scavengers, Reagents, and Metal Scavengers

Biotage scavengers and reagents are based on silica polymers or functionalized polystyrene. These instruments are designed to scale-up commercial applications. 

Based on your experiment requirements, there is a wide range of reagents for you to choose from. A few examples include Biotage® MP-Carbonate, ISOLUTE® Si-Propylsulfonic Acid (SCX-2), and Biotage® PS-TBD.  

Biotage Services

Biotage’s dedicated 1-Point-Support™ team is designed to help you with any product support, repair, or technical document needs you may have.

1- Point Support™

Biotage® 1-Point-Support™ helps customers with their instrument operation, maintenance, and repair-related issuess. Customers can choose from a variety of service agreements based on their needs.  

User Manuals

To ensure success and ease of operation, Biotage provides technical documents for each of its instruments. The documents explain everything, ranging from instrument use and functionalities to maintenanc, and specifications. 

Biotage’s Knowledge Section 

Biotage offers resources in the following four areas:

  • Organic & Peptide
  • Sample Preparation
  • Biomolecules
  • Scale Up

Organic & Peptide

Biotage has curated blogs on several topics around organic and peptide synthesis, including cannabinoid purification, peptide synthesis, flash purification, metal scavenging, and scale-up purification.  

Sample Preparation

Whether it is LC-MS/MS, GC-MS, or any other high-end analytical technique, Biotage has a library of articles on bioanalytical sample preparation. Additionally, they teach you how to choose the right method and approach for your sample.  

Biomolecules

Biotage has efficient automated solutions for plasmid purification, protein purification, synthesis of oligonucleotides, and lipid supply solutions for mRNA and oligo vaccines and therapeutics.

In 2021, Biotage acquired ATDBio Limited to strengthen its position in oligonucleotide synthesis and purification.  

Scale Up

Biotage provides knowledgeable articles focused on scaling-up metal scavenging, Cannabis – CBD/THC remediation, and large-scale flash purification. 

A few examples of its article topics are CBD/THC processing, easy steps to remove palladium, and how to scale up flash purification. 

For more details on the launch of new Biotage equipment and information and resources of its available equipment, visit www.biotage.com.

Lease Synthesis & Purification Equipment with Excedr 

Biotage is a Sweden-based company that manufactures a variety of life sciences, pharma, and biotechnology equipment. It has a spectrum of solutions for sample preparation, biomolecule synthesis and purification, and scale-up metal scavenging and organic synthesis processes.

The company has a dedicated team to help customers with their instrument-related queries including their repair and maintenance. It also provides documents and creates blogs to help its customers with the instrument use and their applications.

Their high-throughput automated equipment not only ensures the production of validated and bulk data but also makes researchers’ lives easier. However, purchasing specialized instrumentation can be costly. You have to pay a huge upfront cost for each product, including service fees and transportation costs, adding up to a hefty downpayment.

These costs make it challenging for laboratories without funding, revenue streams, or large cash reserves to access equipment like Biotage’s.

One effective solution for such a challenging situation is Excedr’s leasing program.

We lease all kinds of equipment, ranging from analytical equipment, clinical instruments, to life sciences and biotech equipment. The repair and maintenance cost of the equipment is also included in our leases.

Don’t have the budget to purchase lab equipment outright? Consider leasing through Excedr to save your lab time and money. Browse your leasing options today!