How Hematology Analyzers Work & How Leasing One Can Benefit Your Lab

Excedr can source all instrument types and accommodate any brand preferences your end-user might have. Request an estimate today and see how leasing can discount your automated hematology analyzer’s price.
All equipment brands/models are available
The Advantages of Excedr’s Hematology Analyzer Leasing Program:
- Eliminates the upfront cost of purchasing equipment by spreading its cost over time
- Minimizes equipment downtime with included complete repair coverage and preventive maintenance
- Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
- Expedites the administrative work needed for instrument procurement and logistics
- Conserves working capital, enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
- Accommodates all manufacturer and model preferences
*Please consult your tax advisor to determine the full tax implications of leasing equipment.

Hematology is the branch of medicine that studies diseases related to blood.
By analyzing a patient’s blood, physicians can reach a general understanding of their health. Hematology also employs more specific testing to screen for and monitor diseases including leukemia, lymphoma, multiple myeloma, as well as types of bleeding disorders such as blood clotting.
Such diseases or disorders can affect any of several components of blood, from blood cells, vessels, and proteins to bone marrow, so measuring these can help diagnose and subsequently treat patients.
Blood count plays a huge role in hematology, which is why hematology analyzers, a type of automated analyzer used specifically to perform complete blood counts, are incredibly important and widely used in medical and clinical laboratories to improve patient care and the healthcare system’s ability to diagnose and treat patients.
A complete blood count (CBC) includes both red blood cells (RBC) and white blood cells (WBC), and can extend to include hemoglobin, platelet counts, and hematocrit levels.
Testing is accomplished at high-throughput rates with precise accuracy using different measurement techniques such as Coulter’s principle, flow cytometry, electrical impedance, and spectrophotometry.
Hematology analyzers, or CBC machines, are designed to perform both small- and large-scale diagnostic testing, integrate with other systems, and provide complete and efficient cell counts.
CBC Machine Types, Uses, & Price

Every hematology analyzer performs a CBC and a 3- or 5-part differential. However, the type of differential depends on the model. Despite the differences in the differential, these analyzers offer automation, high quality results, quality control, and improved point-of-care.
3-Part Differential
Using Coulter’s principle to perform a complete blood count, a 3-part differential hematology analyzer is capable of differentiating between three specific categories of WBCs, or leukocytes.
This includes neutrophils, a type of granulocyte commonly found in all white blood cells, as well as monocytes and lymphocytes, both subtypes of leukocytes. Coulter’s principle requires a sample to be dissolved into an electrolyte solution that is placed inside a container that holds an even smaller container within.
Two pumps are run from the smaller container, one creating a vacuum and the other replacing the solution as it is removed. The vacuum pulls the electrolyte solution containing the WBCs through a small opening in the smaller container.
To measure how many cells pass through, two electrodes are employed. One is placed inside the solution, but outside of the smaller container, and the other is placed within the smaller container.
As the cell passes through the smaller container, an electrical resistance occurs, which is recorded and sent to a computer system which creates a histogram, which approximates the numerical data collected through the complete blood count.
5-Part Differential
This type of cell counter combines Coulter’s principle with flow cytometry, a method of measurement used to understand the characteristics of cells. A 5-part differential cell counter can provide more information on a blood cell using this combination of techniques, providing data on the internal characteristics of a WBC.
Using a laser to scatter light off of a blood cell and measure the scattering at different angles as well as the level of absorption, a cell can be identified. 5-part differential counting includes more types of WBC’s than 3-part differential, however, most tasks in the medical field can be performed using a 3-part differential cell counter.
Analyzer Configuration
It is important to consider several other factors when acquiring a hematology analyzer. Some of those factors include:
- User-friendliness: Most modern devices are easy to use and operate using an intuitive interface
- Size: Many manufacturers offer under-counter or benchtop analyzers. This compact design saves on space.
- Data management: Acquiring a model that effectively stores data prevents extra steps and minimizes human error.
- Time per analysis: It is important to choose a device that can process a test quickly. The time per analysis may vary depending on brand and reaction time for reagents, but is typically very fast when conducting simple CBC counts.
- Microsampling: If sample volume is a concern because it is difficult to collect the required amount of blood samples from a patient for testing, some devices offer microsampling capabilities, so smaller amounts of samples are needed to accurately perform a blood cell count.
We Offer Hematology Analyzer Leases to Fit Every Need

Acquiring a new piece of equipment can be difficult, straining your company’s financial capabilities. Regardless, it is critical to the success of any lab to have the proper equipment. That’s why leasing is a great alternative to buying outright.
We offer a comprehensive lease program which helps your wallet and your peace of mind. Rather than pay a hefty sum upfront, consider spreading your payments out over time to preserve your operating budget. Contact us today to learn more!
If you have an equipment quote from the manufacturer, simply request a lease estimate to begin the lease approval process. Or, if you’d just like to learn more, you can contact us to speak with a team member.
Operating Lease
This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional cash savings.
Sale-Leaseback
If you recently purchased equipment, Excedr can offer you cash for your instrument and convert your purchase into a long-term rental. This is called a sale leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up cash in your budget rather than tying it down to the instrument.
Hematology Analyzer Manufacturers & Models on the Market
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Beckman Coulter:
DxH 500, DxH 520, DxH 600, DxH 690T, DxH 800, DxH 900, DxH Slidemaker Stainer II, UniCel DxH Connected Workcell, COULTER LH 750, COULTER LH 780, COULTER LH 500, COULTER AcT 5diff Autoloader, COULTER AcT 5diff Cap Pierce, COULTER HmX, COULTER LH Series Workstation, AcT diff Analyzer, AcT diff 2 Analyzer, LH 700 Series System, LH 500 Series System
Sysmex America, Inc.:
XN-Series, XN-L Series, XN-1000, XN-1000R, XN-2000, XN-3100, XN-9100, GloCyte CSF Cell Counter, RU-20, XP-300, pocH-100i
HORIBA Medical:
HELO Solution, Yumizen H Series, Pentra 120 Series, Pentra 80 Series, Pentra 60 Series, Micros Series
Abbott Laboratories:
CELL-DYN SAPPHIRE, CELL-DYN RUBY, CELL-DYN EMERALD 22 AL, CELL-DYN EMERALD 22, CELL-DYN EMERALD
Siemens Healthineers:
ADVIA 120 Hematology System, ADVIA 2120i Hematology System with Autoslide, CellaVision DM1200, Hematek 3000 System, ADVIA 360 Hematology System, ADVIA 560, ADVIA 560 AL
Bio-Rad Laboratories:
Variant II Hemoglobin Testing System
ARKRAY USA:
ADAMs A1c, Fully automated hemoglobin A1c analyzer
Diatron Medical Instruments:
Diatron Aquila, Abacus 5, Abacus 380, Abacus 3CT, Abacus Junior 30, Abacus Vet5