How Lyophilizers Work & How Our Program Saves You Time & Money
Excedr can source all equipment types and can accommodate any model preferences your lab might have. Request a quote today and see how a lease can affect your lyophilizer’s price.
All equipment brands/models are available
The advantages of Excedr’s Commercial Freeze Dryer Leasing program:
- Eliminates the upfront cost of purchasing equipment by spreading its cost over time
- Minimizes equipment downtime with included complete repair coverage and preventive maintenance
- Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
- Expedites the administrative work needed for instrument procurement and logistics
- Conserves working capital, enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
- Accommodates all manufacturer and model preferences
*Please consult your tax advisor to determine the full tax implications of leasing equipment.
While the theoretical uses for a lyophilizer, or commercial freeze dryer, are endless, the most common usage is within the biotech, pharmaceutical, food, and technological industries.
Viral vaccines, biological samples, and a variety of other materials used daily benefit from freeze-drying.
The lyophilization process removes water from the material before it is packaged and sealed. This process increases the shelf life of pharmaceuticals, making storage and shipping simple. Reconstituting the dehydrated products is often as simple as adding water or another liquid when required.
Outside of longer shelf life, freeze-dried products maintain their appearance and characteristics, making them invaluable when studying heat-sensitive materials, such as microbes, plasma, proteins, pharmaceutical products, and tissue samples.
Additionally, when freeze-drying samples and products, unique glassware, stainless steel trays, and stoppering tray dryers are generally used in conjunction with the freeze-drying instrument to facilitate sample lyophilization. These products are available from many equipment manufacturers working in the life sciences and pharmaceuticals industries.
The Steps of Cryodessication & A Lyophilizer’s Components
Lyophilizers work on the principle of sublimation, the process of changing ice, a solid, directly into a vapor without entering a liquid state in between. Freeze-drying, also called cryodesiccation or lyophilization, comprises specific steps requiring vacuum pumps and refrigeration.
Vacuum pumps are used to create an ultimate vacuum of below 0.1 mbar. Unlike most dehydration methods, refrigeration is used to provide the low temperatures (in the ULT range) needed to lyophilize a sample, resulting in a better-dried product.
The pump should be sized according to the lyophilizer. If the pump’s flow rate is too high, it will pull vapor through the freeze dryer’s condenser too quickly, reducing the instrument’s efficiency.
It is also essential to clean the condenser after each run to prevent the sublimation of frozen chemicals into the vacuum pump. Chemical resistance requirements for your freeze dryer vacuum pump depend upon the aggressiveness of your solvent.
The general steps of sublimation are as follows:
Pretreating Your Sample
The Freezing Process
Drying Your Sample
Pharmaceutical Freeze Dryer Leases to Fit Every Need
Lyophilizers are an important piece of lab equipment in biotechnology, pharmaceutical, and food and beverage industries. If you’re interested in acquiring a benchtop lyophilizer or console freeze dryer, but are unsure of whether or not purchasing one outright makes sense, consider leasing.
Our lease program is designed to get you the equipment you need without the upfront costs, making cash flow and operating budget management simple. Furthermore, our program is brand agnostic as well, so whether you’re interested in Labconco FreeZone freeze dryers or BUCHI Lyovapor™, we can get you the exact brand you want.
Additionally, if you want to lease other general lab equipment or sample preparation instruments, such as an anaerobic chambers, nitrogen blowdown evaporators, or rotary evaporators, we can help with that too.
Contact us at (510) 982-6552 or fill out our online contact form and we can begin discussing your specific leasing needs.
This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional monetary savings.
If you recently bought equipment, Excedr can offer you cash for your device and convert your purchase into a long-term rental. This is called a sale leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up money in your budget rather than tying it down to a fixed asset.