How Automated Pipetting Works & How Leasing Saves Time & Money

Excedr - Liquid Handlers

No matter what your equipment needs might be, the Excedr lease program can accommodate your end-users brand/model preferences. Request a lease estimate today and see how leasing can save you time and money.

All equipment brands/models are available

Excedr’s Liquid Handler Leasing Benefits Include:

  • Eliminates the upfront cost of purchasing equipment by spreading its cost over time
  • Minimizes equipment downtime with included complete repair coverage and preventive maintenance
  • Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
  • Expedites the administrative work needed for instrument procurement and logistics
  • Conserves working capital,  enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
  • Accommodates all manufacturer and model preferences

*Please consult your tax advisor to determine the full tax implications of leasing equipment.

a microplate well leaning against a graduated cylinder on top of glassware storage

Automated liquid handling instruments & systems are used in various key industries, including forensics, drug discovery and development, molecular biology, agriculture, materials science, and clinical diagnostics.

These precise platforms are designed to move liquids precisely from one vessel to another in applications ranging from DNA/RNA purification and DNA sequencing to high-throughput screening of pharmaceutical compounds. As a technology, it has become a powerful and popular tool in labs throughout the life science industry.

The development and optimization of automated liquid handlers have allowed countless essential techniques to be performed much more quickly and accurately in research and therapeutic applications. For example, manual sample preparation has always been an overwhelming and time-consuming task that creates bottlenecks in your routine lab.

However, scientists and technicians can free up time and achieve consistent and reproducible upstream sample prep by introducing automated liquid handlers into the lab. This has made liquid handlers a cornerstone instrument in any automated laboratory.

For example, research labs where scientists create and use monoclonal antibodies (mAbs) to label and track a wide range of targets require precise liquid handling, something that’s accomplished accurately and repeatably using automated liquid handling platforms.

Additionally, liquid handler lab ware, such as tube racks, tube rack inserts, micro-centrifuge tubes, and cap mats, make your job even easier.

Robotic automation has revolutionized the speed of scientific development and saved countless laboratories time and resources, providing greater reproducibility and eliminating technician-to-technician variability. While every automated liquid handling experiment is unique in terms of throughput, reagents, volumes, order of addition, and readout, several features are central to all liquid handling technologies. We cover those features below.

Liquid Handler Types, Benefits, & Workflow Integration

a hand face up balancing a screw on its index finger

The life sciences and pharmaceuticals industries have greatly benefited from liquid handlers. And although there are a variety of liquid handling robots available, they all serve a similar purpose: provide automated solutions to workflow bottlenecks and increase efficiencies. Below, we cover some of the types available, their benefits, and the workflow integrations used.

Semi-Automatic Pipettors

There are many semi-automated benchtop pipettors available; these offer a more efficient method to manual pipetting that can also reduce the risk of repetitive strain disorder.

Many benchtop pipettors offer precise, semi-automated pipetting, and come equipped with 96 pipetting channels for easy and fast filling of 96- and 384-well microplate well plates, without the use of a computer.

Applications like replication and reformatting, medium exchange, as well as serial dilution, can be executed reproducibly and conveniently using pipettors and dispensers.

 

Automated Pipetting & Automated Dispensers

The simplest types of liquid handlers are automated pipettes or dispensers. Automated dispensers are designed to deliver precise and measured quantities of liquid to microplate well plates.

These instruments range from single-channel devices, which dispense one volume at a time, to multi-channel devices capable of dispensing up to 1536 aliquots simultaneously.

Full automation is most valuable in high-throughput applications that benefit from completely removing human movements. These fully automated liquid handling platforms process hundreds of samples at a time and follow highly complex methods without deviation.

 

Robotic Workstations

More complex systems with built-in robotic functionality have been developed to manipulate the position of the dispensers and containers of automated liquid handling systems. Each system can dispense and sample liquids in tubes or wells accurately, quickly, and repeatably.

By design, these workstations often include automated pipetting systems as well as microplate washers. It is the ability to move and carry out additional functions that differentiate these systems from automated dispensers.

Robotic workstations allow for more automation than can be achieved with a static liquid handler. Furthermore, automated liquid handling robots are often integrated as automated injection modules as the front end of liquid chromatographic systems.

These devices, which save significant amounts of time while reducing error, offer precise sample preparation for high throughput screening/sequencing (HTC), liquid or powder weighing, sample preparation, and bio-assays of many kinds.

 

Fully Integrated Workstations

Lab automation has allowed high-throughput sample preparation, assay preparation, and more by integrating workstations. Fully integrated workstations, much like liquid handling robotics, enable the integration of additional laboratory devices, such as centrifuges, microplate readers, PCR instruments, colony pickers, heat sealers, shaking modules, barcode readers, spectrophotometric devices, storage devices, and incubators.

More complex liquid handling automated workstations can perform multiple laboratory unit operations such as sample transport, sample mixing, manipulation, incubation, and transporting vessels to/from other workstations.

The most common functions of integrated liquid handling workstations include nucleic acid preparation, PCR, next-generation sequencing, ELISA, time-resolved fluorescence, high-throughput screening, assay automation, protein crystallography, solid-phase extraction, and liquid-liquid extraction.

 

Lease a Robotic Workstation to Streamline Your Processes

three shapes shown one after another: an erlenmeyer flask, boiling flask, and graduated cylinder

Laboratory automation has changed the way scientists and researchers perform their work, increasing efficiencies and automating the tedious, repetitive tasks required in life science research, pharmaceutical, and clinical laboratories. 

However, costly upfront costs make procuring modern, necessary equipment difficult. Leasing with Excedr is the creative solution to accessing the expensive equipment you need to perform research, meet funding-related milestones, and stay ahead. 

Our liquid handler leases provide you and your laboratory with the liquid handling solutions needed to increase efficiencies in several workflows, from liquid chromatography to NGS workflows.

We can help your procurement team acquire the best platform for your needs, regardless of the brand. Request a lease estimate for an automated liquid handler system, and we can begin building a custom solution for you right away.

We also offer various automated instruments and system leases, such as auto-samplers, microplate readers, and screening systems. If you want to lease other equipment, it’s as easy as putting together one lease for all instruments.

Operating Lease

This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional monetary savings.

Sale-Leaseback

If you recently bought equipment, Excedr can offer you cash for your device and convert your purchase into a long-term rental. This is called a sale-leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up money in your budget rather than tying it down to a fixed asset.

Liquid Handler Manufacturers & Models
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Eppendorf:
epMotion 96, epMotion 5070, epMotion 5073, epMotion 5075

Labcyte:
Echo 655T, Echo 650T, Echo 525, Echo 555, Echo 550, Echo 520, Access Laboratory Workstation, Access Dual Robot System

Qiagen:
QIAcube HT, QIAxtractor, QIAgility, QIAsymphony SP/AS, QIAxcel, QIAxpert, Rapid Capture System, Hybrid Capture 2, STAR Q Swab AS, QIAsymphony RGQ, STAR Q Punch AS, EZ1 Advanced XL, STAR Q SP/AS

Gilson:
PIPETMAX, qPCR Assistant, Normalization Assistant, GX-241, GX-271, GX-274, GX-281, 223 Sample Changer, Automated Fly Food Dispenser

TTP Labtech:
mosquito crystal, mosquito LCP, mosquito HTS, mosquito HV, mosquito X1, dragonfly crystal, dragonfly discovery

Beckman Coulter:
Biomek 4000, Biomek NXP, Biomek FXP, Biomek i5, Biomek i7

BioTek:
Precision Pipetting System, EL406, MultiFlo FX, 405 TS, 405 LS, ELx405, ELx50, MicroFill

Tecan:
Fluent, Freedom EVO, Freedom EVOlyzer, D300e Digital Dispenser, CEREX IP8, IPT Plate Transport, Ultravap Mistral, CEREX ALD III 48, CEREX ALD III 96

Hamilton Company:
Microlab NIMBUS, Microlab STAR Line, Microlab VANTAGE, NGS STAR, chemagic STAR, NIMBUS Select, Genomic STARlet, MassSTAR, Bioanalytical STARlet, easyPunch, easyBlood, ELISA NIMBUS, VeriSeq NIPT Microlab STAR, ID STARlet, ClonaCell EasyPick, AutoLys STAR, Decapping STAR, Microlab 600, Microlab 300, LabElite DeCapper

Thermo Fisher:
CV 2000, Versette, Multidrop, AutoMate Express, KingFisher Flex System, KingFisher Duo Prime

PerkinElmer:
Sciclone G3, JANUS G3, cell::explorer, Zephyer G3, Twister III, plate::handler II

Aurora Biomed:
VERSA 10, VERSA 110, VERSA 1100

Hudson Robotics:
PlateCrane, LabLinx, PA1000, SOLO, Micro10x, RapidWash, FilterPress, RapidHit Automated HitPicking System, ProLink Express, Synthetic Biology Workstation, VaryScreen

Formulatrix:
Mantis, Tempest

Agilent:
AssayMAP, Vertical Pipetting Station, PlateLoc, BenchCel, Direct Drive Robot, Microplate Labeler, Microplate Centrifuge, BenchBot Robot, Bravo NGS, NGS Workstation

Tomtec:
Quadra4, Quadra2, Quadra Tower, Quadra Wash 2, AutoSeal, Harvester 96, Autogizer, Autogizer2

Art Robbins:
Scorpion, Phoenix, Cobra, Hydra, Gryphon

Metrohm:
846 Dosing Interface, Dosimat plus

Analytik Jena:
GeneTheatre, Cybio SELMA, Cybio FeliX, CyBio Drop

Roche:
cobas 6800, cobas 8800, cobas 4800, cobas AmpliPrep, cobas TaqMan System, MagNA Pure 96, MagNA Pure 24, cobas p 630, cobas p 480, cobas s 201

ELITech Group:
ELITe InGenius

Abbott:
ACCELERATOR p540, ACCELERATOR a3600

Ortho Clinical Diagnostics

Bio-Rad:
QuickStep ELISA Processor

Fluidigm:
C1, Callisto

Stratec:
InviGenius, InviGenius PLUS

 

Operating Capital Benefits

Operating Capital Benefits

Excedr's operating lease structure allows you to keep your business credit line open for expansions, staffing, and other operational expenses. Additionally, it strengthens the cash flow of your business and keeps cash reserves free for business development opportunities.

Effects on Credit

Effects on Credit

Leasing / renting provides you with non-dilutive financing and does not hinder your future borrowing ability. You're able to acquire the equipment you need without the baggage associated with traditional financing.

Speed of Approval

Speed of Approval

Excedr's program allows you to respond quickly as your need for equipment and technology arises. You can be approved with minimal documentation and have the equipment you need in operation and generating revenue for your business quickly.

Refurbished Equipment

Refurbished Equipment

Unlike traditional financing and leasing companies, the Excedr program can accommodate refurbished equipment in addition to demo units. If you are looking for additional cost-savings, we recommend considering this option.