Liquid chromatography diagram

Liquid Chromatography Systems

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Analytical diagram

Reduce complexity in compound analysis—lease liquid chromatography systems for precise separation and quantification.

These versatile systems have evolved significantly and are essential in numerous analytical workflows.

The foundation of liquid chromatography (LC) lies in separating compounds within a sample based on their interactions with the mobile phase (solvent) and the stationary phase (chromatographic packing material). Higher pressures were adopted using smaller particles, leading to the development of high-performance liquid chromatography (HPLC).

In an HPLC system, a pump and mobile phase work together to move the sample mixture (analyte) through the column at high pressure. Compounds interact with the mobile and stationary phases, separating based on affinity or polarity. The retention time of each compound depends on its interactions.

HPLC’s remarkable sensitivity allows it to identify trace compounds at parts per trillion (ppt), making it indispensable in pharmaceuticals, environmental monitoring, forensics, and the chemical industry.

Now, let’s delve deeper into the world of liquid chromatography systems. In this blog post we’ll cover:

  • System components: Pumps, mobile and stationary phases, and more. We’ll also cover how they are used to achieve precise separation and analysis.
  • Different instrument and system types: HPLC, UHPLC, and FPLC and their applications in scientific and industrial fields.
  • The diverse uses of each system type: Applications of LC systems, from analyzing pharmaceutical compounds to characterizing complex protein structures, empowering researchers to choose the right tool for their needs.
  • Pricing ranges: The general costs of a basic setup and the prices of different liquid chromatography systems.

By the end of this blog post, you’ll gain valuable insights into liquid chromatography systems, allowing you to make informed decisions about the equipment you use and achieve exceptional results in your analytical endeavors, whether you’re an experienced chromatographer or a newcomer.

Why Biotech Teams Choose Excedr

Here’s what sets our leasing program apart.

Leasing Built for Biotech Startups

Our program is designed specifically for life sciences—flexible, non-dilutive, and aligned with the needs of R&D-heavy teams.

Non-Dilutive Capital to Scale Faster

Leasing helps extend your runway without giving up equity. Fund your lab and hit key milestones without compromising ownership.

You Bring the Equipment—We Finance It

We don’t carry inventory. Once approved, you choose the exact equipment you need—we’ll structure the lease around it.

Fast Approvals for Fast-Moving Teams

Our startup-savvy process gets you approved in days—not weeks—so you can move at the pace of your science.

Terms That Match Your Timeline

Leases range from 2 to 5 years, tailored to your stage, equipment lifecycle, and budget.

Expert Support from Day One

We work directly with vendors and service providers to streamline logistics, repairs, and maintenance—so you don’t have to.

No Loan-Like Terms or Restrictions

Skip the covenants, collateral, and IP pledges. Our leases are founder-friendly by design.

Free Up Capital with Sale-Leasebacks

If you’ve already purchased equipment, we can buy and lease it back to you—converting upfront costs into flexible monthly payments.

Flexible Options at Lease-End

Choose to renew, return, or purchase at fair market value—no pressure, just options.

Popular Liquid Chromatography Equipment Manufacturers

Agilent
1220 Infinity II
Agilent
1220 Infinity II Analytical-Scale
Agilent
1260 Infinity Amino Acid Analysis
Agilent
1260 Infinity II
Agilent
1260 Infinity II Analytical Scale
Agilent
1260 Infinity II Bio-Inert Analytical Scale
Agilent
1260 Infinity II Prime
Agilent
1290 Infinity II
Agilent
1290 Infinity II Bio Online
Waters Corporation
ACQUITY Arc
Waters Corporation
ACQUITY Arc MDLC
Waters Corporation
ACQUITY Premier
Waters Corporation
ACQUITY UPC2
Waters Corporation
ACQUITY UPLC H-Class PLUS
Waters Corporation
ACQUITY UPLC I-Class PLUS
Waters Corporation
ACQUITY UPLC M-Class
Cytiva
AKTA avant
Cytiva
AKTA go™
Cytiva
AKTA pcc
Cytiva
AKTA pilot
Cytiva
AKTA process™ CFG
Cytiva
AKTA pure
Cytiva
AKTA ready
Cytiva
AKTA ready XL
Cytiva
AKTA ready™ 450
Waters Corporation
Alliance HPLC
Waters Corporation
Alliance iS
Waters Corporation
Arc HPLC
Waters Corporation
Arc Premier
GL Sciences
Auto BPR
Cytiva
BioProcess Modular Systems
Waters Corporation
Breeze QS HPLC
Danaher Life Sciences
CESI 8000 Plus ESI-MS
GL Sciences
Dual Plunger Pump KP-22 Series
Danaher Life Sciences
ExionLC™ 2.0
GL Sciences
Intelligen Pump UI-22 Series
PerkinElmer
LC 300 HPLC
PerkinElmer
LC 300 UHPLC
Waters Corporation
LC Prep 150
Waters Corporation
LC Prep AutoPurification
Jasco
LC-4000 RHPLC
Jasco
LC-4000 Series
Jasco
LC-4000 UHPLC
Jasco
LC-4000-MS
Jasco
LC-4500
Danaher Life Sciences
M5 MicroLC
Waters Corporation
Modular Systems
PerkinElmer
NexSAR™ HPLC
Jasco
Preparative HPLC Systems
Jasco
Tandem LC-MS Systems
Thermo Fisher Scientific
Transcend LX
Thermo Fisher Scientific
Transcend TLX
Gilson
VERITY® CPC Lab
Gilson
VERITY® CPC Lab MS
Gilson
VERITY® CPC Pilot
Gilson
VERITY® SKID
Thermo Fisher Scientific
Vanquish Analytical Purification
Thermo Fisher Scientific
Vanquish Core
Thermo Fisher Scientific
Vanquish Duo
Thermo Fisher Scientific
Vanquish Flex
Thermo Fisher Scientific
Vanquish Horizon
Thermo Fisher Scientific
Vanquish Inverse
Thermo Fisher Scientific
Vanquish Loop
Thermo Fisher Scientific
Vanquish Method Development
Thermo Fisher Scientific
Vanquish Neo
Thermo Fisher Scientific
Vanquish Online
Thermo Fisher Scientific
Vanquish Simple Switch
Thermo Fisher Scientific
Vanquish Tandem
Thermo Fisher Scientific
Vanquish Trap
Agilent
Agilent
Bio-Rad
Bio-Rad
Cytiva
Cytiva
Danaher
Danaher Life Sciences
Gilson
Gilson
GL Sciences
GL Sciences
Jasco
Jasco
Novasep
Novasep
Shimadzu
Shimadzu
PerkinElmer
PerkinElmer
Thermo Fisher Scientific
Thermo Fisher Scientific
Waters Corporation
Waters Corporation

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