Bio-layer interferometry (BLI) diagram

How Bio-Layer Interferometers Work & How We Save You Time & Money

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All equipment brands and models are available.

Bio-layer interferometry, or BLI, is an optical analytical technique that observes the associative and dissociative interaction of molecules.

In chemistry, it is important to know the affinity, thermodynamic properties, and stoichiometry of a substance, or analyte. BLI provides this data by observing and measuring biomolecular interactions, particularly protein interactions, in vitro. It is an important tool in a wide variety of fields.

Using white light, BLI looks at how molecules bind to or disengage from other molecules. Because it is also a label-free technique, it does not use any isotopes that would chemically bind to and label proteins. These features make BLI highly useful for applications such as fragment screening, kinetic characterization, and real-time label-free chemical binding measurements. It is considered a strong alternative to Surface Plasmon Resonance (SPR), however, in comparison, it does have its advantages and disadvantages.

Why Biotech Teams Choose Excedr

Here’s what sets our leasing program apart.

Leasing Built for Biotech Startups

Our program is designed specifically for life sciences—flexible, non-dilutive, and aligned with the needs of R&D-heavy teams.

Non-Dilutive Capital to Scale Faster

Leasing helps extend your runway without giving up equity. Fund your lab and hit key milestones without compromising ownership.

You Bring the Equipment—We Finance It

We don’t carry inventory. Once approved, you choose the exact equipment you need—we’ll structure the lease around it.

Fast Approvals for Fast-Moving Teams

Our startup-savvy process gets you approved in days—not weeks—so you can move at the pace of your science.

Terms That Match Your Timeline

Leases range from 2 to 5 years, tailored to your stage, equipment lifecycle, and budget.

Expert Support from Day One

We work directly with vendors and service providers to streamline logistics, repairs, and maintenance—so you don’t have to.

No Loan-Like Terms or Restrictions

Skip the covenants, collateral, and IP pledges. Our leases are founder-friendly by design.

Free Up Capital with Sale-Leasebacks

If you’ve already purchased equipment, we can buy and lease it back to you—converting upfront costs into flexible monthly payments.

Flexible Options at Lease-End

Choose to renew, return, or purchase at fair market value—no pressure, just options.

Popular BLI Manufacturers

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Octet® R8
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Octet® RH16
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Octet® RH96
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Request an Initial Lease Estimate Today

Ready to lease? Speak with one of our leasing specialists to begin the application process.