How Immunohistochemistry Staining Works & How We Save You Time & Money
Despite the diversity in methods and applications, our lease program is able to source all instrument types and can accommodate any brand preferences your end-user might have. Request an estimate today and see how leasing can discount your autostainer’s price.
All equipment brands/models are available
The Advantages of Excedr’s IHC Instrument Leasing Program:
- Eliminates the upfront cost of purchasing equipment by spreading its cost over time
- Minimizes equipment downtime with included complete repair coverage and preventive maintenance
- Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
- Expedites the administrative work needed for instrument procurement and logistics
- Conserves working capital, enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
- Accommodates all manufacturer and model preferences
*Please consult your tax advisor to determine the full tax implications of leasing equipment.
Immunohistochemistry (IHC) staining is typically accomplished using manual staining methods.
However, developments in automation have led to a much more efficient workflow, providing high-throughput sample preparation and staining.
These high-throughput devices are called automated immunohistochemistry stainers, IHC stainers, autostainers, or automated slide stainers, and provide greatly increased turnaround times. They come in various formats, from compact benchtop models to larger fully open systems.
IHC staining is critical to several applications and plays an important role in pathology and histology by detecting the presence of specific protein markers. These markers use antibodies that bind with specific antigens to help accurately classify and diagnose abnormal cells, such as those found in cancerous tumors. Antigens are a type of protein found throughout certain cells.
The diagnosis these markers provide can be used to determine whether or not a cancerous tumor is benign or malignant, as well as the cancer’s severity, among other medical analyses.
IHC can also be used for basic research, including the study of biomarker distribution and localization and distinctly expressed proteins in different parts of the body, along with normal tissue and organ development, pathological processes, and cell death and repair.
Furthermore, IHC staining has become a complementary technique to H&E staining, short for hematoxylin and eosin, and Special Stain techniques.
While H&E and Special Stain are non-specific, IHC provides the ability to stain specific protein markers. You will also see scientists and researchers combine in-situ hybridization (ISH) methods with immunostaining to generate more complete pictures of protein and mRNA expression in specific tissue sections and cell types.
ISH is a unique molecular analysis method because it provides the precise microscopic localization of DNA, mRNA and microRNA.
IHC Stainer Preparation, Benefits, & Price
There are different approaches and variations in immunohistochemistry, however, the main preparative steps are as follows:
The Evolution of Autostainers
We Offer Automated IHC Staining Leases to Fit Every Need
If you want to increase your immunostaining throughput capabilities and meet larger testing demands, switching to an automated IHC staining system is the best way to change that. Automated slide staining systems prrovide clinical, pathology, and histology labs with the ability to meet increased demand without comprising quality.
That said, if purchasing an automated stainer outright is an issue, consider leasing as an alternative! By leasing your lab equipment, you can alleviate the issues that equipment procurement generally produce, such as high upfront costs and hidden fees.
We offer a comprehensive lease program that can greatly benefit your lab and provide you with solutions that bypass the traditional pain points of the up-front costs of expensive laboratory equipment.
Lastly, if you’re interested in further streamlining your workflow, consider leasing an automatd coverslipper with us as well. An automated coverslipper offers you the ability to efficiently mount your histological slides with a cover slip.
Request a lease estimate today and begin the simple and quick process of leasing your next IHC stainer.
This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional cash savings.
If you recently purchased equipment, Excedr can offer you cash for your instrument and convert your purchase into a long-term rental. This is called a sale leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up cash in your budget rather than tying it down to the instrument.