Nucleic Acid Extraction & Purification & How We Save You Time & Money
Excedr can source all equipment types and can accommodate any model preferences your lab might have. Request a quote today and see how a lease can discount your DNA purification machine price.
All equipment brands/models are available
The Advantages of Excedr’s Automated Nucleic Acid Instrument Leasing Program:
- Eliminates the upfront cost of purchasing equipment by spreading its cost over time
- Minimizes equipment downtime with included complete repair coverage and preventive maintenance
- Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
- Expedites the administrative work needed for instrument procurement and logistics
- Conserves working capital, enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
- Accommodates all manufacturer and model preferences
*Please consult your tax advisor to determine the full tax implications of leasing equipment.
Nucleic acid extraction and purification are basic yet key methods used in research across molecular biology, biopharmaceuticals, biotechnology, and various medical sciences.
Nucleic acid sample preparation includes a wide range of extraction and purification techniques that are used to transform a sample from one that can’t be directly analyzed into one that can, thus fitting the specific requirements of the analytical technique being performed downstream. It is highly important to purify and extract your samples when planning on performing quantification and quantitation of nucleic acids.
That’s because purity and yield of the extracted nucleic acids is critical to performance in those downstream applications, which include polymerase chain reaction (PCR)—more specifically, real-time PCR (qPCR)—as well as reverse transcription PCR (RT-PCR) and sequencing. In clinical and research laboratories today, RNA, DNA, and total nucleic acids (total RNA and DNA) are isolated and extracted through both manual and automated techniques.
Manual extraction requires multiple steps, increasing the risk of contamination. It is also considered highly complex, so not every laboratory technician is capable of performing extraction and purification manually.
That being said, another downside to manual extraction is that the entire process is extremely time consuming and labor-intensive, requiring the undivided attention of the technician.
Automated extraction, on the other hand, has many benefits over more traditional manual methods. The most important being the consistency of the isolated nucleic acid. Sample manipulation and reagent use is reduced, significantly decreasing the chance of cross-contamination.
Additionally, automated instruments and systems reduce the overall complexity of extraction and purification, making testing easier to perform by a larger number of scientists.
And while automated extraction instruments have many benefits over manual methods, the cost per test can be drastically higher than manual methods. Automation also only typically makes sense when a high throughput of samples is required.
Knowing your and your team’s exact sample preparation needs is an important step in deciding which method—whether it is manual or automated—as well as which instrument, is right for your lab.
Below we will cover some of the techniques and characterization methods available, as well as the basics of DNA purification.
Extraction & Purification Methods
Nucleic acid extraction and purification are the essential first steps for countless downstream applications, as high quality, highly pure DNA and RNA is important in a wide variety of research and clinical applications. Extraction and purification can be performed using either manual or automated methods. We will cover the basic steps of these methods below.
Manual Nucleic Acid Isolation
Automated Nucleic Acid Isolation
Genomic vs. Plasmid DNA Isolation
Automated DNA & RNA Extraction Instrument Leases to Fit Every Need
The need to increase accuracy and speed has pushed the importance of automation to the forefront of the life sciences and molecular biology in particular.
Minimizing human intervention and increasing efficiencies in the lab has escalated as a result of events like the COVID-19 pandemic, with laboratories striving hard to develop diagnostics and therapeutics to fight the virus while having to do so with a limited number of scientists and technicians.
Finding ways to automate nucleic acid purification to increase throughput, reproducibility, and accuracy, while also processing samples with a high degree of purity, has been crucial in this effort.
Connect with us at +1 888-927-3802 or complete our contact form and we can discuss all your extraction and purification needs in further detail.
This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional monetary savings.
If you recently bought equipment, Excedr can offer you cash for your device and convert your purchase into a long-term rental. This is called a sale leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up money in your budget rather than tying it down to a fixed asset.