How Microplate Spectrophotometers Work & How We Save You Time & Money

Excedr - Microplate Readers

Request a lease estimate today and see how leasing with Excedr can reduce your high throughput microplate reader’s price. We are able to procure all equipment types and can accommodate any brand preferences your lab might have.

All equipment brands/models are available

The Advantages of Excedr’s Microplate Reader Leasing Program:

  • Eliminates the upfront cost of purchasing equipment by spreading its cost over time
  • Minimizes equipment downtime with included complete repair coverage and preventive maintenance
  • Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
  • Expedites the administrative work needed for instrument procurement and logistics
  • Conserves working capital,  enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
  • Accommodates all manufacturer and model preferences

*Please consult your tax advisor to determine the full tax implications of leasing equipment.

a cell, a microplate well, antibodies, and a dot with 6 lines through it

Microplate readers are used to detect biological, chemical, or physical events—as well as properties and analytes—within the device’s well plates via the measurement of light.

Plate readers/detectors are found in a wide variety of laboratories and see extensive use in numerous applications across a wide range of disciplines, including:

  • Life sciences 
  • Basic research
  • Target discovery/Lead discovery
  • Bioassay validation
  • Quality control
  • Drug safety
  • Toxicity testing
  • Biopharmaceutical and pharmaceutical manufacturing processes

Furthermore, plate readers are found in both industrial and academic settings, as well as food, cosmetics, and environmental research. 

Depending on the manufacturer, plate readers can be equipped with a 96- or 384-well microplate or a standard cuvette, and can handle large amounts of samples in minutes or even seconds thanks to a wide range of well formats and multi-channel optics. 

Furthermore, the use of robotic microplate stackers increases throughput. If your lab is in need of high-throughput screening (HTS) and detection, microplate readers are an excellent addition to your lab. Automation is a key feature and allows for integration into automated systems and workflows.

Plate readers help reduce operational time while saving on reagent costs as well, allowing researchers and scientists to spend more time on data analysis.

Microplate Reader Detection Modes, Applications, & Price

an outstretched hand face up holding the end of a DNA double helix

Sometimes called microplate spectrophotometers or photometers—these singe- and multi-mode instruments work similarly to spectrophotometers, however, the method of photometry used differs. 

While a standard spectrophotometer only measures one sample at a time in a cuvette, an absorbance plate reader can measure the same application with much higher throughput. 

Readers largely differ by the type of detection mode they offer. Samples that are pipetted into the wells produce, convert, or transmit light signals that are detected using a photomultiplier tube (PMT). The PMT converts the photons into electricity that is then quantified by the plate reader.

The most common detection modes include: 

  • Absorbance (Visible and UV-Vis)
  • Fluorescence intensity
  • Luminescence 

Readers may also include additional detection modules such as those for: 

  • AlphaScreen®
  • Nephelometry

Depending on the optical signal changes that occur during a reaction, samples may need to be excited by light at specific wavelengths. Detection mode is based on the type of excitation that needs to occur to detect a signal. 

Plate readers support various wavelength ranges. To ensure only specific wavelengths are used, the light produced by the light source is selected by a specific excitation filter or monochromator.

Excitation light is usually provided by a broad band xenon flash lamp, however, detecting luminescence doesn’t require a light source as the samples emit light on their own through chemical or biochemical reactions. 

Increasing sensitivity and specificity can also be controlled by filters or monochromators, however, these devices are usually placed between the sample and detector.

Research-Based Applications

Readers are found everywhere in research, as they help facilitate improved processes and efficiency, as well as minimized operational time. Some of the research-based applications these devices are used for include:

  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Protein and Nucleic Acid Quantification
  • Kinetics
  • Protein Assays
  • Cell Density, Viability, Proliferation and Cell Death
  • Fluorescent Protein Assays
  • Gene Expression

Drug Discovery Based Applications

These devices are also highly useful in the area of drug discovery and development. This includes:

  • Live-Cell Assays
  • Phenotypic Screening
  • Amplified Luminescent Proximity Homogeneous Assay Screen (AlphaScreen)
  • Homogeneous Time-Resolved Fluorescence (HTRF)

Absorbance Microplate Reader Leases To Fit Your Lab’s Needs

a petri dish with a sample inside

In terms of plate reader price, it truly varies. Simpler scanners that only have one detection module are relatively affordable. If you increase the number of detection modules, the cost rises proportionally. 

However, technology has vastly improved over the years and there are now competitively priced microplate readers out on the market. Whatever your research needs, Excedr can help. 

From microplate readers to spectrophotometers and cell imaging multi-mode microplate readers, we have you covered. Connect with us by calling +1 888-927-3802 or filling out our contact form to specify your equipment leasing needs.

Operating Lease

This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional monetary savings.


If you recently bought equipment, Excedr can offer you cash for your device and convert your purchase into a long-term rental. This is called a sale-leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up money in your budget rather than tying it down to a fixed asset.

Plate Reader Manufacturers & Models on the Market
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Infinite 200 PRO, Infinite M Nano, Infinite M Nano Plus, Infinite F Nano Plus, Infinite M Plex, Infinite F Plex, Infinite M1000 PRO, Spark, Sunrise, Infinite F50, Infinite Lumi

PHERAstar FSX, CLARIOstar Plus, POLARstar Omega, LUMIstar Omega, FLUOstar Omega, Omega Series, SPECTROstar Omega, SPECTROstar Nano, NEPHELOstar Plus

TTP Labtech:

Synergy Neo2, Cytation, Synergy H1, Synergy 2, Synergy HTX, PowerWave HT, Epoch 2, Epoch, ELx808

Molecular Devices:
SpectraMax iD3, SpectraMax iD5, SpectraMax i3x, SpectraMax M Series, MiniMax 300, Paradigm, QuickDrop, 340PC384, Plus 384, 190, SpectraMAx L Series, VersaMax, EMax Plus, Gemini EM, Gemini XPS, FlexStation 3, FilterMax F3, FilterMax F5

Thermo Fisher Scientific:
Varioskan LUX, Fluoroskan Ascent, Fluoroskan Ascent FL, Luminoskan, Multiskan FC, Multiskan GO

Berthold Technologies:
Mithras LB 940, Mithras² LB 943, TriStar² LB 942, TriStar² S LB 942, Centro XS³ LB 960, Centro LB 960, Centro PRO LB 962, Orion II, Apollo 11 LB 913

VICTOR, EnSight, EnVision 2105, ViewLux

xMark, iMark, PR 3100 TSC, PW 41, EVOLIS, Model 1575, Model 680

GloMax Explorer, GLoMax Discover, GloMax Navigator, GloMax 20/20


and more!


Operating Capital Benefits

Operating Capital Benefits

Excedr's operating lease structure allows you to keep your business credit line open for expansions, staffing, and other operational expenses. Additionally, it strengthens the cash flow of your business and keeps cash reserves free for business development opportunities.

Effects on Credit

Effects on Credit

Leasing / renting provides you with non-dilutive financing and does not hinder your future borrowing ability. You're able to acquire the equipment you need without the baggage associated with traditional financing.

Speed of Approval

Speed of Approval

Excedr's program allows you to respond quickly as your need for equipment and technology arises. You can be approved with minimal documentation and have the equipment you need in operation and generating revenue for your business quickly.

Refurbished Equipment

Refurbished Equipment

Unlike traditional financing and leasing companies, the Excedr program can accommodate refurbished equipment in addition to demo units. If you are looking for additional cost-savings, we recommend considering this option.