- Spreading out payments over time eliminates the upfront cost of equipment purchases
- Payments may be 100% tax deductible*, which yields you significant cash-savings
- It costs less to lease through our program than to purchase outright
- We minimize instrument downtime with our complete repair coverage
- Excedr handles the admin work associated with equipment procurement and maintenance
- With the cash saved through our program, labs are better able to reinvest in their core business and operations (staffing, inventory, marketing/sales, etc.)
*Please consult your tax advisor to determine the full tax implications of leasing equipment.
All equipment brands/models are available
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Duplicating cultured microbial samples is done when working with or studying microorganisms. Colony picking, either automated or done manually, describes an instrument that picks microbial colonies out of a solid medium and reproduces them into a separate media. In instances where wide spectrum testing is needed to be performed, it is easy to see why having possibly thousands of identical samples to test is useful. Food testing, biofuels, genome editing, microbiology, and immunotherapy are just a few areas that benefit from the use of colony pickers, also known as colony arrayers. Whether it is for mass specimen testing, large-scale cloning of hybrid cells for antibodies or hybridomas, or DNA sequencing, colony pickers are highly useful tools to assist in your lab space.
Automating this process has been a huge leap in helping scientists further in their work. Hand-picking bacterial cultures used to take hours, and for tasks as complex as sequencing the human genome, this is prohibitively tedious. In addition to the massive amount of time it would take to complete, the high probability of human error often made the work useless. Luckily, colony picking has been fully automated to be both fast and accurate. Using imaging software, a picker accurately identifies the necessary colonies that are to be copied and transfers part of the organism to a separate medium to grow. The transition from using a single pin to a picking head equipped with multiple independently controlled pins has also sped up the duplication process. Though the core functionality has not changed much, automation has allowed scientists to go from reproducing a few hundred bacteria in a day to hundreds of thousands in a day. Colony pickers are used with colony counters, which are able to count the number of microbial colonies that are in a sample.
Colony Arrayer Applications, Advantages, & Costs
Colony pickers provide specific applications for research and study, some of which we will cover here:
DNA Sequencing & DNA Analysis
In DNA analysis, to find the order of the nucleotide bases, DNA sequencing must be performed. This research is important to advancing knowledge in various biology fields. To perform DNA sequencing the sample genome must be broken down into smaller pieces, cloned, mixed with other material, rebuilt, and analyzed to determine its sequence. Using a colony picker, specifically for the cloning phase in the process, more gene samples can be replicated meaning larger DNA strands can be analyzed.
Microbial testing in the food industry is very important. Using colony pickers scientists can screen thousands of samples of food products for dangerous bacteria and mold quickly. Due to certain food’s shelf life, rapid testing is vital to ensure that the integrity of the food is not compromised. The testing of yeast, mold, bacterial colony cell growth, and other pathogens in dairy products also poses the additional problem of needing to keep the sample cold. Having fast colony preparation and testing ensures that additional impurities are not introduced in this testing phase
Immunotherapy is an important technique in treating cancer. This biological therapy boosts a person’s immune system by using living tissues to duplicate cancer-fighting substances. Monoclonal antibodies, or mAbs, are one such type of treatment that benefits greatly from the use of colony pickers. In this treatment, researchers create specific antibodies that target specific antigens found on cancer cells. In order for this to be effective, tens of thousands of these mAbs need to be made in a relatively short period of time. This treatment is effective due to the huge throughput of mAbs and monoclonal hybridoma colonies that a picker can create.
Advances in DNA Technology
When the human genome was mapped it marked a huge step in our understanding of ourselves. This discovery has helped progression in multiple existing fields of study as well as opened up many new fields of study. Genetic engineering, once thought to be science fiction, has become very real. Similar techniques to those involved in the charting of human DNA are used to break down and change parts of our genetic code. Companies such as CRISPR have even given people the ability to do simple gene editing in their own homes. Colony pickers have not only contributed to the advancements in our knowledge of our own DNA, but have also continued to be of use to us in altering them now. A vital piece of equipment, one should not have to debate whether they can or cannot afford to go without a colony picker.
Let us at Excedr take care of your equipment needs. Our leasing program can help make your lab as efficient as possible. With repair and preventative maintenance coverage, we can also minimize your downtime, and give you peace of mind. Contact us today!
We Offer Colony Picker Leases to Fit Every Need
This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional monetary savings.
If you recently bought equipment, Excedr can offer you cash for your device and convert your purchase into a long-term rental. This is called a sale leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up money in your budget rather than tying it down to a fixed asset.
COLONY ARRAYER MANUFACTURERS & MODELS ON THE MARKET
- Hudson Robotics; RapidPick, RapidPick Complete, RapidPick Lite, RapidPick SP Single Pin Colony Picker, RapidPick Harvester
- Molecular Devices: QPix 400 Series, QPix 420, QPix 450, QPix 460, ClonePix 2, Colony Counter, CloneSelect Imager
- Bulldog Bio: Cell Counter, IncuCount, RSIC150
- Tecan: Pickolo, GFPickolo, PickoloCell, PetriPlater
- Stuart Equipment: Colony Counter SC6PLUS
- Oxford Optronix: GelCount
- Synbiosis: ProtoCOL 3, Protos 3, ProcScan, aCOLyte 3 HD, aCOLade 2
- Pol-Eko Aparatura: LKB 2002
- IUL Instruments: SphereFlash, DOT
- Reichert Technologies Analytical Instruments: Quebec Darkfield Digital, Quebec Darkfield Manual
- InterScience International: Scan 400, Scan 1200, Scan 500, Scan 300, ScanStation 100, ScanStation 200
- Kbiosystems: K6-3, K8
- Singer Instruments: PIXL, PIXL-001, The Stinger, Rotor HDA, PhenoBooth
- and more!
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Effect on Credit & Operating Capital
Leasing/renting does not hinder your future borrowing ability and allows you to keep your business credit line open for expansions, staffing, and other operational expenses. Additionally, it strengthens the cash flow of your business and keeps cash reserves free for business development opportunities.
Unlike traditional financing and leasing companies, the Excedr program can accommodate refurbished/reconditioned equipment in addition to demo units. If you are looking for additional cost-savings, we recommend considering this option.
Speed of Approval
Excedr’s program allows you to respond quickly as your need for equipment and technology arises. You can be approved with minimal documentation and have the equipment you need in operation and generating revenue for your business quickly.