How Rotary Evaporation Works & How We Save You Time & Money

Excedr Analytical Instruments Rotary Evaporator

Despite the diversity in methods, the Excedr lease program is able to source all instrument types and can accommodate any brand preferences your end-user might have. Request an estimate today and see how leasing can discount your rotovap’s price.

All equipment brands/models are available

The Advantages of Excedr’s Rotovap Leasing Program:

  • Eliminates the upfront cost of purchasing equipment by spreading its cost over time
  • Minimizes equipment downtime with included complete repair coverage and preventive maintenance
  • Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
  • Expedites the administrative work needed for instrument procurement and logistics
  • Conserves working capital,  enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
  • Accommodates all manufacturer and model preferences

*Please consult your tax advisor to determine the full tax implications of leasing equipment.

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Rotary evaporation is accomplished using a rotary evaporator, also known as a rotovap or rotavap.

It is a commonly used technique for separating a compound of interest from a low-boiling solvent, such as an organic, inorganic, or polymeric substance. 

Separation is accomplished by heating a mixture of solvent and compounds inside an evaporation flask, while partially submerging it in a warm water bath. The glassware is simultaneously rotated in the bath and subjected to a reduced pressure environment via a vacuum pump.

Rotary evaporators evaporate and condense the solvent, effectively separating it from the mixture. The desired compound is the only thing left behind, which will be used for a downstream application. 

Rotovaps are standard fare in organic chemistry because of their sample concentration and solvent distillation capabilities, and are commonly utilized in chemical and pharmaceutical laboratories for extraction processes, sample preparation, R&D, and more.

Rotovap Components & Prices

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Rotary evaporators range in size and volume capacity, with options available to meet space and usage specifications, as well as digital displays for ease of use. Performance and quality control are important in any lab, so understanding how a rotary evaporator operates will help to inform your decision-making. 

The main components that affect the performance of evaporation include the rotary motor, vacuum pump, condenser, water bath, and various glassware. Depending on a laboratory’s evaporation needs, some scientists rely on centrifugal evaporators to simultaneously evaporate multiple samples. Let’s take a look at the common components of a rotovap.

Rotary Motor
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The motor unit rotates an evaporation flask containing the sample. Spinning the flask increases the surface area of the solvent and the rate of evaporation, and reduces the possibility of a solvent boiling or erupting suddenly. Accidents do happen though. Because of this, many rotovap manufacturers offer replacement rotary evaporator glassware.

Eruptions that occur during evaporation are referred to as bumping, and can lead to contamination. It is important to consider your motor’s rotational speed and the effect that it will have on your other equipment.

A rotovap attains speeds of 10-280 rpm, but anywhere between 250-280 rpm is considered an optimal speed. Some devices offer speeds above 300 rpm, which will generate higher rates of efficiency, but greater chances of unwanted wear-and-tear.

 

Vacuum Pump & Controller
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A vacuum pump is a necessary part of the evaporation process. Using one during evaporation substantially reduces the pressure in the evaporation system. Reducing pressure is necessary because it lowers the boiling temperature of the solvent, allowing for quicker evaporation. Some models will include a vacuum pump. But, you might find out that you have to acquire the pump separately.

It is important to understand what kind of vacuum pump is best suited for your applications. Using the wrong pump can lead to numerous issues, such as inefficient evaporation, equipment damage, safety risks, or solvent loss.

A vacuum pump, a vacuum controller, or regulator, is another key part of the evaporation process. Using it helps ensure you have the right level of pressure within your system. If it’s too high, the vacuum pump won’t be doing its job of speeding up evaporation. And if the pressure is too low, you could see bumping or foaming.

Like eruptions, or bumping, foaming is an issue that can arise during evaporation. Foaming results from surfactants being present in sample, which causes foam to appear. It can be manually dealt with by releasing the stop cock whenever foam appears. However, a vacuum pump and controller can help automate the process and reduce bumping and foaming.

Furthermore, having precise control over the pressure of your system means you can find the optimal pressure for the desired evaporation rate and more easily create a reproducible process. Having a vacuum controller also reduces the need to make other adjustments, such as altering the water bath temperature.

Similar to pumps, you may see vacuum controllers built into some rotovap models. This feature often bumps up the equipment’s price by a significant amount though.

 

Condenser
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This component, a type of glassware, is used to condense gas vapors during the evaporation process. By cooling the vapor down using a localized cold surface, the condenser turns the gas back into a liquid.

Condensers are usually made of glass, and come in a variety of configurations that are ideal in evaporation processes because of their ability to reduce solvent loss.

The two main types of condensers used in rotary evaporators are Dimroth condensers and cold fingers. Rotovaps have a flask or catch that captures the condensed liquid. Typically, a chiller will be used alongside the condenser to keep temperatures low during evaporation by cooling water and recirculating the liquid to the condenser.

Some evaporation systems will include a chiller, however, not every instrument comes with a chiller. It simply depends on the model you are leasing.

 

Fluid Bath
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A water bath, or heating bath, is used to heat the sample. The evaporation pulls heat from the solution, so it is important to replace that heat in order to maintain a constant temperature and continue the process. Using a water bath provides a lower temperature, ensuring that the solution does not become damaged.

The temperature of the water bath should not exceed the boiling point of the solvent. In most cases, 40-60°C is sufficient. If the temperature is too high, the condenser may be overloaded, as the rate of evaporation exceeds its capabilities.

 

Rotary Evaporator Glassware
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The glassware included with a rotary evaporator include the receiving flask, the condenser (covered above), and a collection flask, or receiving flask.

 

Centrifugal Evaporators
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While a rotary evaporator is only capable of processing one sample at a time, a centrifugal evaporator is capable of evaporating solvents from multiple samples simultaneously. This technique involves a vacuum pump attached to a centrifuge chamber to reduce pressure and lower the boiling point of the sample.

Centrifugal force is applied through spinning to ensure even heat dispersion and to prevent any boiling over, or “bumping”. Similar to a rotovap, this machine evaporates solvents quickly while preventing any damage.

 

Rotary Evaporator System Leases to Fit Every Need

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Whether you work in the fields of chemistry, pharmaceuticals, or biochemistry, rotary evaporators are an essential part of everyday preparation. Although it can be a financial burden to purchase a piece of equipment outright, there are alternatives, such as equipment leasing and financing.

Excedr offers a comprehensive leasing program complete with preventative maintenance and repair coverage; the perfect solution for all your equipment procurement needs.

Our program helps you bypass the burdensome acquisition of new equipment by spreading out payments over time, ensuring that your cash flow doesn’t face disruptions. If you want to lease a rotary evaporator, let us know. We’ll put together a lease estimate based on your manufacturer quote.

Additionally, if you need to lease a rotary evaporator chiller to ensure appropriate cooling for your rotary evaporator, we can put the two units together on one lease, making both procurement and management that much simpler. Reach out to learn more.

Operating Lease

This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional monetary savings.

Sale-Leaseback

If you recently bought equipment, Excedr can offer you cash for your device and convert your purchase into a long-term rental. This is called a sale-leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up money in your budget rather than tying it down to a fixed asset.


Rotary Evaporator Manufacturers & Models on the Market
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BUCHI:
Rotavapor R-300, Rotavapor R-100, Rotavapor R-220 Pro, Rotavapor R-250, Rotavapor R-220 EX, Rotavapor R-250 EX, Rotavapor R-220 High Performance, MultiVapor P-6/P-12

Ecodyst:
EcoChyll X9, EcoChyll X7, EcoChyll X5, Ecochyll X3, EcoChyll X1, Ecodyst 1H, EcoChyll S

Across International:
AI SolventVap 5L to 50L Series, SolventVap 2L, SolventVap 5L, SolventVap 10L, SolventVap 20L, SolventVap 50L

KA:
RV 3 V, RV 3 V-C, RV 3 Flex, RV 3 with Dry Ice Condenser, RV 3 with Dry Ice Condenser coated, RV 8 V, Rv 8 V-C, RV 8 Flex, RV 8 with Dry Ice Condenser, RV 8 with Dry Ice Condenser coated, RV 10 digital V, RV 10 digital V-C, RV 10 digital Flex, RV 10 digital with Dry Ice Condenser, RV 10 digital with Dry Ice Condenser coated, RV 10 auto V, RV 10 auto V-C, RV 10 auto Flex, RV 10 auto pro V, RV 10 auto pro V-C, RV 10 auto pro Flex

Heidolph Instruments GmbH & Co. KG:
Hei-VAP Core, Hei-Vap Expert, He-Vap Ultimate, Hei-Vap Expert Control, Hei-Vap Ultimate Control, Hei-Vap Industrial, Hei-Vap Industrial B

Cole-Parmer/Stuart Equipment:
Cole-Parmer Rotary Evaporator System, RE400, RE401, RE402

Yamato:
RE202 Series, RE202, RE202-E, RE212-D, RE301 Series, RE601 Series, RE601A-O, RE601A-W, RE601B-O, RE601B-W, RE601C-O, RE601C-W, RE801 Series, RE801A-O, RE801A-W, RE801B-O, RE801B-W, RE801C-O, RE801C-W

EYELA:
N-1300EVS Series, N-1200BV Series, N-1200BS Series, N-1200BT Series, N-4000, N-4000H, N-4000W, N21, N51, N-101 Series

LabTech, Inc.:
EV311H, EV311, EV311-Plus, EV311 ADV, EV311 VAC, EV400H, EV400, EV400 Touch, EV400 VAC, YRE-2020Z

Hydrion Scientific:
RE-350, RE505, RE510

 


Operating Capital Benefits

Operating Capital Benefits

Excedr's operating lease structure allows you to keep your business credit line open for expansions, staffing, and other operational expenses. Additionally, it strengthens the cash flow of your business and keeps cash reserves free for business development opportunities.

Effects on Credit

Effects on Credit

Leasing / renting provides you with non-dilutive financing and does not hinder your future borrowing ability. You're able to acquire the equipment you need without the baggage associated with traditional financing.

Used Equipment

Used Equipment

Unlike traditional financing and leasing companies, the Excedr program can accommodate refurbished/reconditioned equipment in addition to demo units. If you are looking for additional cost-savings, we recommend considering this option.

Speed of Approval

Speed of Approval

Excedr's program allows you to respond quickly as your need for equipment and technology arises. You can be approved with minimal documentation and have the equipment you need in operation and generating revenue for your business quickly.