How Particle Analyzers Work & How We Save You Time & Money
Despite the diversity in methods, the Excedr lease program is able to source all instrument types and can accommodate any brand preferences your end-user might have. Request an estimate today and see how leasing can discount your particle counter’s price.
All equipment brands/models are available
The Advantages of Excedr’s Particle Analyzer Leasing Program:
- Eliminates the upfront cost of purchasing equipment by spreading its cost over time
- Minimizes equipment downtime with included complete repair coverage and preventive maintenance
- Takes advantage of potentially 100% tax deductible* payments, providing you significant cash-savings
- Expedites the administrative work needed for instrument procurement and logistics
- Conserves working capital, enabling you to reinvest in your core business and operations (staffing, inventory, marketing/sales, etc.)
- Accommodates all manufacturer and model preferences
*Please consult your tax advisor to determine the full tax implications of leasing equipment.
Studying the properties of particles or powders of a wide variety of materials (polymers, plastics, aerosol spray, cement, and so much more) can provide scientists with vital information about industrial processes that involve these samples.
In fact, particle characterization and analysis is extremely important in chemical engineering and material sciences. The devices that perform these analyses are referred to as particle size analyzers.
Particle analyzers have taken up a role in many fields, however, these systems have flourished particularly well in industrial processes since the turn of the century. Most industrial energy processes require in-depth knowledge of particles and powders and their interactions with their environment.
It is important to note that there are internationally recognized standards labs should meet depending on the material they are working with. Doing so shows an organization’s competency in performing particle analysis. These standards include specific ISO, such as ISO 13320:2020.
Besides adhering to certain standards and requirements, particle technology, as a whole, is used to calculate different properties of a particle and how they will act under certain conditions. This information is critical in various industries and helps each area of study or manufacturing achieve unique, highly-important goals.
Alongside chemical engineering and material sciences, areas of use for particle and powder technology are in the pharmaceutical and biopharmaceutical industries, in nanoparticle systems, emulsions, and even bubble systems. That being said, whichever industry you’re involved in, whether it be industrial, pharmaceuticals, chemical, biology, agriculture, or another industry, knowing which instrumentation best fits your lab’s needs is essential to successful particle analysis results.
Particle Counters, Analysis, & Applications/Industries
Particle counters and sizers work to provide researchers an accurate count of how many particles are in a substance at a given time and offer quality control (QC) and quality assurance (QA) testing. They are able to perform a variety of tasks across a number of industries, some of which we will cover below.
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It is important to get an accurate count of your sample when working with powders or bulk amounts of small objects, as well precise particle size measurement.
In the petroleum industry, there are strict codes and regulations that dictate what is in oil, which means monitoring the amount of particulate in it is a vital process. The mechanism for how these small particles are counted changes depending on the size of the powder.
Most of the techniques, however, involve light scattering, light obscuration, or directly imaging the particles. Due to their dependence on light, these methods are referred to as optical counters. Additionally, depending on what substance the powders are in, specific particle counters are used.
- Aerosol: Aerosols are defined as solids particles suspended in a liquid or a gas. A common example of an aerosol would be hairspray. Aerosol particle counters are specifically made to look at the number of particulates in the air. This can be extremely useful in determining the air quality of an area or for maintaining cleanrooms.
- Liquid: Maintaining clean water, ensuring the quality of injectable drugs, and monitoring oil purity can all be achieved using liquid particle counters. When a liquid is passed through one, they are able to determine its purity and how much particulate matter is contained in it. Water purity and hydraulic oil cleanliness are both heavily regulated and keeping track of them is important.
- Solid: Solid, or dry particle counters, are used to monitor and determine how much of a particular substance is in a mixture of other solid powders. Geology and the mining industry offer some of the simplest particle counters; sieves.
Particle Size Analysis
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Other than knowing how many particles are in a substance, knowing how large they are is also very important. Having a full picture of particle size distribution is important.
Particle size analysis or more simply, particle sizing, is a technique that is used to find either the size range or average size of particles in a powder or liquid sample. The most simple example of a particle sizer would be a sieve. How a sizer actually works will depend on a wide range of factors such as the desired size range, the chemical composition of the sample, and how much of the sample is being tested on.
Laser diffraction is one of the most common methods used to perform particle shape analysis. By observing how light scatters when a laser passes through a dispersed particulate sample, its relative size can be determined. Smaller particles will result in light scattering at larger angles, while larger particles will scatter light at smaller angles.
Besides laser diffraction, light scattering methods are available, including static light scattering (SLS), multi-angle light scattering (MALS), and dynamic light scattering (DLS). Additionally, there are other established techniques—high definition image processing, gravitational settling of particles, and dynamic image analysis (DIA)—used to determine shape parameters and size distribution.
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Diffraction methods and light scattering are just a few of the methods used in real-time particle size analysis. Using automated, real-time particle size analysis methods allow researchers to perform applications like sticky-wet concentrated slurries, liquid emulsions, and dry particulate streams.
Most importantly, real-time—or on-line—particle size analysis, provides optimal performance in the particle analysis process. By using on-line analysis, the frequency of measurement can increase significantly and enable the delivery of a reliable and efficient data stream. This is just one benefit to real-time analysis methods.
Other benefits include increased efficiency and return on investment (ROI), as well as lower energy costs and real-time control. Furthermore, on-line methods provide troubleshooting capabilities, an improved process development, and reduced operator risk.
Real-time particle analyzers can perform both count and size analysis, and are highly useful in industrial settings. A few examples include bulk mineral processing and cement manufacturing.
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Besides the petroleum, mining, and cement industries, particle size analysis is commonly used in the pharmaceuticals and biopharmaceutical sectors.
Nanoparticle size analyzers are used to determine both the size and size distribution range of individual particles for a given sample. The pharmaceutical industry uses these analyzers because the size and shape of a particle can affect how a medication works in the body. Furthermore, determining size and distribution range can help optimize the drug development and manufacturing processes.
Nanoparticle size analyzers are capable of measuring particles in many ways, similar to that of a typical counter or sizer. The methods used in nanoparticle size analysis include light scattering, laser diffraction (or real-time analysis), photon correlation, and spectroscopy. Furthermore, fluorescence labeling can be used to help distinguish specific nanoparticles within a complex background or, alternatively, to identify certain unknown particles in a sample by binding fluorescently labeled antibodies to those target particles. By combining fluorescence labeling with nanoparticle size analysis (size, concentration, etc.), researchers are able to perform nanoparticle tracking analysis (NTA).
This is important within the field of medicine due to characterization requirements of nano-sized particles used to carry drugs, such as polymer-based/virus-like particles or lipid-based carriers, as well as macromolecular drugs that include proteins, peptides, DNA, or RNA which are delivered by injection.
Lastly, these particular particle size analyzers often have the ability to process wet or dry dispersions, measure concentration and zeta potential, and perform aggregation, making them a perfect fit for the pharmaceutical and biopharmaceutical industries.
The Large Hadron Collider
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Probably the most well-known application of particle technology is the Large Hadron Collider at the CERN institute. Their work involving quantum physics is truly fascinating, although their scientific endeavors rarely affect fields of study other than science. This is exactly what happened with a radiation sensor named Timepix.
It was first developed for the Large Hadron Collider, and was going to detect, count, and study radiation particles in the Collider. In spite of that, it was eventually moved off-world in order to detect the same radiation particles in astronauts aboard the ISS. Its next task, however, would be in the artistic world, where it would be used to find forged paintings.
Finding fake art used to be a very specialized industry where an authenticator would need intimate knowledge about the artist’s handwriting, style, and tools that they used. Today, art authenticators are still a very specialized group of people but they now employ the latest scientific tools to help them with their work. Timepix’s ability to isolate individual pigments to analyze the authenticity of paintings goes well beyond what ancient authenticators ever used.
We Offer Particle Sizer Leases to Fit Every Need
Excedr’s lease program has solutions for a wide range of analytical instruments. Whether it be a particle analysis device such as the Mastersizer 3000 from Malvern Panalytical, or a different analyzer (thermal or TOC), we can help.
Call us at (510) 982-6552 or fill out our contact form online and we can start to discuss in more detail your exact equipment leasing needs, as well as the benefits of our lease program.
This off-balance sheet financing structure provides three options at the end of the term. The lessee has the option to return the equipment to the lessor, renew at a discounted rate, or purchase the instrument for the fair market value. Monthly payments are also 100% tax deductible which yields additional monetary savings.
If you recently bought equipment, Excedr can offer you cash for your device and convert your purchase into a long-term rental. This is called a sale leaseback. If you’ve paid for equipment within the last ninety days, we can help you recoup your investment and allow you to make low monthly payments. This also frees up money in your budget rather than tying it down to a fixed asset.
Particle Counter Manufacturers & Models on the Market
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Thermo Fisher Scientific:
Partica LA-960, Partica mini LA-350, ViewSizer 3000, SZ-100 Nanoparticle series, CAMSIZER, CAMSIZER X2, PSA300, ParticleFinder, OBS-ONE Pn, MEXA-2000SPCS series, PR-PD2BLI, PR-PD2HR, PR-PD5, PR-PD2, PR-PD3, AP-370 series, APDA-372
Archimedes, Insitec range, Mastersizer 3000, Mastersizer 3000E, Morphologi range, NanoSight range, Parsum range, Zetasizer range, Spraytec
MET ONE 3400, MET ONE 6000, MET ONE HHPC+ SERIES, MET ONE 7000, MET ONE 6000P, MET ONE Facility Monitoring Systems, Vi-CELL BLU Cell Viability Analyzer, Multisizer 4e Coulter Cell Analyzer, Vi-CELL MetaFLEX, Vi-CELL XR, Z Series Coulter Counter, Multisizer 3 Coulter Counter, LS 13 320 XR Particle Size Analyzer, DelsaMax Series, LS 13 320 Particle Sizing Analyzer, SA 3100, HIAC 8011+, HIAC 9703+, HIAC PODS+ Portable, HIAC ROC
SALD-2300 Laser Diffraction, SALD-7500nano Laser Diffraction, IG-1000 Plus Induced Grating
ANALYSETTE 22 NanoTec, ANALYSETTE 28 ImageSizer, Module A-22
Zetasizer range, Zetasizer Ultra, Zetasizer Pro, Zetasizer Nano Family, Subseieve AutoSizer (SAS), Elzone II 5390, SediGraph III Plus, Particle Insight, Saturn DigiSizer II
Sync, Bluewave, S3500, Tri-Blue, Nanotrac Wave II, Nanotrac Wave II Q, Nanotrac Flex, Zetrator, PartAn3D, PartAn3D Maxi, SI, DustMon, PartAn3D Pro, PartAn SI Pro
Hosokawa Micron Powder Systems:
Mikro Air Jet Sieve model MAJSx2, Powder Characteristic Tester PT-X, Labomixer LV, Viblette VBL Wet Sieve Analyzer, Peneto Analyzer PNT-N
Litesizer 100, Litesizer 500, PSA Series
Vibrational Sieve Shakers, Air Jet Sieving Machine AS 200 jet, Tap Sieve Shaker AS 200 tap
Haver & Boecker:
CPA 2-1 HR, CPA2-1, CPA 2 Conveyor, CPA 2-1 Online, CPA 4-1, CPA 4-2, CPA 4 Conveyor
Angstrom Advanced Inc.:
AP-100 Dynamic Image, AP-200 Static Image, AP-300 Intelligent Laser, AP-400 Intelligent full automatic wet&dry laser, AP-500 Intelligent Dry Laser, AP-600 Laser, AP-900 NANO Laser
PC3400, PC4400, PC6 with HYDROACT series, PC3 with HYDROACT series, PC5000
Grimm Aerosol Technik:
CPC Family, SMPS+C Family, SMPS+E, PMP CPC Family, Sky CPC, EDM 465, 7917 Emission Sampling System, 11-D, 11-S Sky-OPC, 1371 MiniWRAS, EDM 164, EDM 180, EDM 665
RODOS, HELOS, QICPIC, NIMBUS, NANOPHOX, OPUS, MYTOS, PICTOS & Co.
PSI 3001, PSI 5001
FC200S+HR, CF200MHR, FC200TC, FC200P-HR, Ipac 2, 500 Nano, Zephyr LDA, 500 nano XY, Zephyr ESR 2, Morpho 3D, Scan 700, Sievecal, CDD270
380, DiSCmini, NanoMet3
Gray Wolf Sensing
TES Electrical Electronic Corp.
2200 PCX, Lasair III 110, Lasair III, IsoAir 310P, Nano-ID NPC10, Airnet II 4 Channel, Airnet II(s) 2 Channel, Chem 20, Ultra DI 20, Ultra DI 50, UltraChem 100, UltraChem 40, LiQuilaz II S Series, LiQuilaz II E series, HSLIS-M65e, HSLIS-M100e, HSLIS-M50E, CLS-700 T Corrosives, APSS-2000 Parenteral, AirSentry II Mobile, AirSentry II Multi-Point, AirSentry II Point-of-Use Ion Lighthouse Worldwide Solutions: ApexZ, ApexZ3, ApexZ50, Apex Portable, ApexP3, ApexP5, ApexRemote, SOLAIR, SOLAIR 1100LD, Solair 3350, Solair 5100, Boulder Counter, NanoCount, NanoCount 30, NanoCount 50, NanoCount 65C, Batch Sampler LS-20, Batch Sampler LS-60, ActiveCount Series, ActiveCount100, ActiveCount100H, ActiveCount25H, ActiveCountR, ActiveCountRp
LaserNet 200 Series
AeroTrak Cleanroom 9001, AeroTrak 9303-01, AeroTrak 9306-V2, AeroTrak Portable 9110-01, AeroTrak Portable 9310-02, AeroTrak Portable 9350-02, AeroTrak Portable 95001-01, AeroTrak Portable 9510-02, AeroTrak Portable 9550-02, BIOTRAK Real-Time Viable 9510-BD
5000 Series AQM, 7000 Series AQM, 7000 Series, 5000 Series, 8000 Series, 2000 Series
LAP 322, LAP 340, FAS 362, PAM 510, PAP 610, PAP 612